Primary Hyperaldosteronism: Typical Clinical Manifestations

Clinical Manifestations of Primary

Primary hyperoxaluria is characterized during life by a continuous urinary oxalate excretion level of about 100-400 mg. (expressed as (COOH)2.2H20) per 24 hours as opposed to the normal value of less than 45 mg. per 24 hours. Patients with this disease usually present in early childhood with multiple bilateral renal or ureteric calculi which increase rapidly in size and are composed wholly or p...

Genetics of primary hyperaldosteronism.

Hypertension is a common medical condition and affects approximately 20% of the population in developed countries. Primary aldosteronism is the most common form of secondary hypertension and affects 8-13% of patients with hypertension. The two most common causes of primary aldosteronism are aldosterone-producing adenoma and bilateral adrenal hyperplasia. Familial hyperaldosteronism types I, II ...

Rhabdomyolysis due to primary hyperaldosteronism.

Rhabdomyolysis may be secondary to trauma, excessive muscle activity, hereditary muscle enzyme defects and other medical causes. Primary hyperaldosteronism is characterised by hypertension, hypokalemia, suppressed plasma renin activity, and increased aldosterone excretion. Rhabdomyolysis is not common in primary hyperaldosteronism. We report here a 42-year-old woman presenting with rhabdomyolys...

Renal calculi in primary hyperaldosteronism.

Increased urinary calcium (Ca++) excretion and the presence of negative Ca++ balance is well documented in primary hyperaldosteronism. However, renal calculi as a major manifestation of this disorder is not previously described. This report describes probably the first patient who presented with renal calculi in association with primary hyperaldosteronism. We believe that primary hyperaldostero...

[Primary hyperaldosteronism due to adrenal adenoma].